Endocrine Abstracts

BackgroundTo date, available animal models have failed to replicate the complex pathophysiology of chronic diabetic wounds. In a recent study we administered a regimen of antioxidant enzyme inhibitors (AIE) to develop a reliable and effective murine model. Here we use this model to test the efficacy of an amniotic membrane (AM) scaffold.Methods30 db/db mice received a pre-established AIE regimen and a 1 &#215...